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Leighann Sullivan, Ph.D. candidate
Bennett Lab George R. Brown Hall W222 and W223 (713)-348-3304 |
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Leighann Sullivan, Ph.D. candidate
Bennett Lab George R. Brown Hall W222 and W223 (713)-348-3304 |
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The aim of my thesis work is to characterize the expression, function, and regulation of two members of a novel family of proteins specific to Clostridium acetobutylicum. These proteins appear to be regulated by Spo0A, a known master transcriptional regulator, at the transition to solventogenesis. Gel Photo of the heterologous over-expression of Proteins 1 and 2. I direct three other projects with which I have undergraduate assistance. The first project is aimed at the heterologous expression of genes responsible for acetoin production in E. coli. The second project is focused on metabolic engineering for the in vivo production of b-hydroxybutyrate. The third project investigates the use of metabolic engineering to increase production of H2 in C. acetobutylicum.
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C. acetobutylicum metabolic pathways:
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